Programme Oocyte2019

Wednesday 16 January 2019

15:00-17:00        Arrivals, registration, putting up posters


17:00-19:30        Welcome get-together & buffet


Session 1: Germ cells and the entry into oogenesis

Chair: E. Houliston


19:30-19:50 Gary Wessel (Brown University, USA): Specification mechanisms for precursors of the oocyte, the Primordial Germ Cells


19:50-20:20 Mayu Inaba (University of Connecticut, USA): Nuclear envelope phosphatase is essential for asymmetry formation during Drosophila germline stem cell division.

20:10-20:30 Valentina Baena (University of Connecticut, USA): Three-dimensional organization of cytoplasmic projections in mouse ovarian follicles.


20:30-20:50 Jean-Réné Huynh (Collège de France, France): Early stages of germ cell development in adult Drosophila.


20:50-21:10 Zak Swartz (MIT, USA): Prophase I-arrested oocytes actively replenish CENP-A nucleosomes to maintain centromere identity.


21:10-21:30 Laurent Meijer (ManRos Therapeutics, Roscoff France): From worm and starfish oocytes to clinical drugs, a journey from sea to pharmacy.


21:30-21:50 Michal Brouze (Polish Accademy of Sciences, Poland): The role of TENT5 poly(A) polymerases in mouse oogenesis.


Thursday 17 January 2019

Session 2: Early events of oocyte maturation

Chair: L. Jaffe


9:00-9:30   Takeo Kishimoto (Ochanomizu University, Japan): In commemoration of the half-centennial anniversary: 1-Methyladenine identification in starfish oocytes and beyond. Sponsored by The Company of Biologists Ltd.


9:30-10:00     Hiroko Shirai: Past and present research.


10:00-10:20 Noriyo Takeda (Asamushi Marine Station, Japan): Maturation and sperm release-inducing hormone in the hydrozoan jellyfish.


10:20-10:40 Evelyn Houliston (LBDV,  France): Regulation of oocyte maturation in the hydrozoan Clytia hemisphaerica.


10:40-11:10 Coffee break


11:10-11 :30 Jeremy Egbert (University of Connecticut, USA): Calcium dynamics in intact mouse ovarian follicles.


11:30-11:50 Aude Dupré (Sorbonne Université, France): To divide or not: the PKA-ARPP19 module and Cdk1 activation in Xenopus oocytes.


11:50-12:10 Jacek Kubiak (University of Rennes, France): The role of CDC6 in regulation of the first embryonic M-phase entry in Xenopus laevis and mouse.


12:10-12:30 Enrico Daldello (UCSF, USA): Cyclin B2 is a component of pre-MPF and is required for progression through the meiotic cell cycle in mouse oocyte.


12:30-14:00  Lunch 


14:00-16:00  Poster session 1 

Session 3: Centrioles, spindles and actin

Chair: E. Christians

16:00-16:20 Greenfield Sluder (University of Massachusetts Medical School, USA): Control of centrosome inheritance in starfish: RSK activity in the suppression of the maternal.

16:20-16:40 Marie Pierron (EPFL, Switzerland):  Dissecting centriole inactivation in starfish and C. elegans oocytes.


16:40-17:00     Julien Dumont (Institut Jacques Monod, France):  Specific Adaptations of the Chromosome Segregation Process in C. elegans Oocytes.


17:00-17:20 Janet Chenevert (LBDV, France): Spindle positioning in the early ascidian embryo.


17:20-17:50 Coffee break


17:50-18:10 Marie-Emilie Terret (Collège de France, France): Aberrant low cortical tension generates chromosome misalignment in oocyte.


18:10-18:30 Guillaume Halet (University of Rennes, France): Cofilin regulates actin network homeostasis in mouse oocytes.


18:30-18:50 Binyam Mogessie (University of Bristol, UK): Actin-based mechanisms of chromosome segregation in mammalian eggs.


18:50-19:10 Peter Lenart (MPI, Göttingen): Unexpected functions of the actin cytoskeleton in meiotic divisions of oocytes


20:00-22:00 Dinner in town of Villefranche  

Friday 18 January 2019


Session 4: Cell cycle regulation through meiosis and embryogenesis

Chair: R. Dumollard


9:00-9:20   Kazuyoshi Chiba (Ochanomizu University, Japan): Meiosis reinitiation and apoptosis of starfish oocytes/eggs.


9:20-9:40       Stefania Castagnetti (LBDV, France): Mitotic control of early embryonic divisions.


9:40-10:00  Ryusaku Deguchi (Miyagi University of Education, Japan): Oocyte maturation and spawning of light- and dark-type medusae of the hydrozoan Cladonema pacificum.


10:00-10:20 Takahito Hoshi (Tokyo Institute of Technology, Japan): Molecular phylogenetic analysis and hybridization in light-type and dark-type Cladonema pacificum.


10:20-11:00 Coffee break


11:00-11:20 Katja Wassmann (Sorbonne Université, France): Oocytes cycling through meiosis.


11:20-11:40 Eulalie Buffin (Sorbonne Universite, France): Meiosis under tension: the error correction pathway in mouse oocyte.


11:40-12:00 Duygu Özpolat: Sister cell lineages have distinct cell cycle characteristics the marine annelid Platynereis: Quiescent germline, fast cycling mesoderm, and slow cycling growth.


12:00-12:20 Benjamin Lacroix (Institut Jacques Monod, France): Spindle Size and Assembly Timing Regulation by Microtubule Dynamics During Early Embryonic Cleavages.


12:30-14:00  Lunch 


14:00-16:00  Poster session 2 

Session 5: Preparing the egg for fertilisation

Chair S. Castagnetti


16:20-16:40 Marco Conti (UCSF, USA): Dual program of translation activation and termination during oocyte reentry into the meiotic cell cycle.


16:40-17:00 Nancy Standart (Cambridge University, UK): Conserved regulators of translation and mRNA decay: from Xenopus oocytes to human cell lines.


17:00-17:20     Lisa Mehlmann (University of Connecticut, USA): SNARE Proteins are Required for Maintenance of Meiotic Arrest and Cortical Granule Exocytosis in Mouse Oocytes.


17:20-18:00 Coffee break


18:00-18:20 Monika Fluks  (University of Warsaw, Poland): Unfinished transcription in immature mouse oocytes leads to aberrant Ca2+ homeostasis regulation at metaphase II stage.


18:20-18:40 Keith Jones (University of Adelaide, Australia): Meiotic drive in oocytes maybe due to inherent spindle asymmetries.


18:40-19:00 Johne Liu (Ottawa University, Canada): Calcium nanodomains in spindles.


20:00-22:00 Dinner in town of Villefranche  


Saturday 19 January 2019


Session 6: Fertilisation

Chair: A. McDougall


9:00-9:20   Masahito Ikawa (Osaka University, Japan): New Insights into the Molecular Events of Mammalian Fertilization.


9:20-9:40       Karl Swann (Cardiff University, UK): The mechanisms of PLCzeta induced Ca2+ oscillations in mammalian egg activation.


9:40-10:00 Mark Johnson (Brown University, USA): HAP2(GCS1) initiates gamete fusion by insertion into female gamete plasma membranes.

10:00-10:20 Juliette Fedry (Utrecht University, The Netherlands): HAP2 membrane interaction - Novel insight into the molecular mechanism of gamete fusion.


10:20-11:00 Coffee break


11:00-11:20 Ken-ichi Sato (Kyoto Sangyo University, Japan): In vitro reconstitution of ovulation/maturation, fertilization and postovulatory aging in Xenopus laevis oocytes and eggs.


11:20-11:40 Thomas U. Mayer (University of Konstanz, Germany): Calcineurin promotes APC/C activation at meiotic exit by acting on both XErp1 and Cdc20.


11:40-12:00 Christophe Arnoult (Université Grenoble Alpes, France): PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice.


12:00-12:20 David Burgess (Boston College, USA): Mechanism of Sperm Aster Migration Varies Based on State of Meiosis at Fertilization.


12:30-13:30  Lunch 


13:30             Take down posters and departures.

Institut de la Mer de Villefranche (IMEV)

CNRS - Sorbonne Université

181 chemin du Lazaret

06230 Villefranche-sur-Mer - FRANCE

©2018 by F.Bekkouche